Wednesday, November 30, 2022
HomeCovid-19SARS-CoV-2 Antibodies in Infants Born to Women with COVID-19 Decline Rapidly

SARS-CoV-2 Antibodies in Infants Born to Women with COVID-19 Decline Rapidly

SARS-CoV-2 antibody may not stay longer, particularly in infants, reports a recent article published in Emerg Infect Dis journal on July 3, 2020

A new study shows that COVID-19 antibody may not stay longer, particularly in infants. The study results were published in the journal Emerg Infect Dis on July 3, 2020.

SARS-COV-2 IGG IGM

The study was conducted in Wuhan, China. In the investigations, researchers evaluated (SARS-CoV-2)–specific antibodies, IgM and IgG, in 64 infants born to women who were admitted to Tongji Hospital from January 19–April 12, 2020.

Of all the 64 babies, 24 babies, with gestational ages ranging from 31 weeks to 41 weeks, were born to SARS-CoV-2-infected mothers. RT-PCR methods confirmed the infection. On the other hand, 40 infants (gestational age from 35 weeks, three days, to 41 weeks, three days) were born to women without COVID-19.

Of the 24 infants who were born to women with COVID-19, 15 (62.5%) had detectable IgG, and 6 (25.0%) had detectable IgM; nucleic acid test results were all negative. None of the 24 infants had complications related to pneumonia.

The investigators found that the IgG level gradually decreased in all15 infants with positive IgG. However, in babies who were IgM positive, IgG levels declined more slowly.

All babies had negative nucleic acid test results. The babies that were born to women without COVID-19, the results of nucleic acid tests from the throat and anal swab specimens, and the results of antibody assays were negative.

The study was limited by the small sample size. However, the findings show a rapid rate of decline in antibody titers, suggesting a lack of passive protective immunity in infants, and IgM detection in infants, supporting a growing body of evidence of possible vertical transmission, the study concluded.

Related Publication and Further Readings

Gao, J., W. Li, et al. (2020). “Disappearance of SARS-CoV-2 Antibodies in Infants Born to Women with COVID-19, Wuhan, China.” Emerg Infect Dis 26(10).

LEAVE A REPLY

Please enter your comment!
Please enter your name here

Recent Post

Biodiversity Ghana Savana

Oil Palm Development Threatens African and Latin American Biodiversity, New Reports...

0
New research suggests that zero deforestation pledges may leave important habitats, biodiversity in Latin America and Africa vulnerable to agricultural growth.

MOST COMMENTED

fitness-vegan-exercise

For Weight Loss, Vegan Is Better Than the Mediterranean Diet

51
Vegan is more effective for weight loss, cholesterol control, body composition, and insulin sensitivity, when compared head to head with Mediterranean diet.

RECENT UPDATE

Antioxidant Flavonols Are Associated with Slower Memory Deterioration

A study published online in the journal Neurology suggests that consuming or drinking more flavonol-rich foods, such as fruits, vegetables, tea, and wine, may prevent memory loss.

Oil Palm Development Threatens African and Latin American Biodiversity, New Reports Warns

New research suggests that zero deforestation pledges may leave important habitats, biodiversity in Latin America and Africa vulnerable to agricultural growth.

Immigrants to Canada Have Lower Strokes

Immigrants to Canada have a 33% lower rate of stroke than long-term residents, according to a study published in the August 18, 2021, online issue of Neurology.

Frequent Wildfires Linked to Human-Caused Climate Change

Scientists show that climate change has been the leading cause of wildfires that destroyed a growing amount of land in the western U.S. over the past two decades.

Cooking Food: Researchers Find the Oldest Proof of Controlled Fire Use

According to researchers, the bones of a massive carp fish date the earliest indications of cooking by prehistoric people to 780,000 years ago.